详细剧情
布拉德皮特和安吉丽娜朱莉所扮演的史密斯夫妇在外人眼里是一对令人羡慕的夫妻，他们家境优越，夫妻恩爱。但多年的夫妻生活却多少磨平当初的激情，而多些许平淡与乏味，而这一切都仅仅是假象而已，这夫妇二人都是受过专业训练，身经百战，杀人无数的职业杀手。他们各自效力于对立的两个秘密组织，可能由于双方都是伪装技法高超的超级杀手，虽然同室而居七年有余，但各自却对对方的秘密身份知之甚少。而在一次执行刺杀任务中，夫妇二人恰好被同时指派去刺杀同一个目标，这使得二人为完成任务不得不同室操戈，而结果却是两败俱伤。为了找到导致自己任务失败的对方，夫妇俩开始调动一切资源调查对方的身份，而随着调查的深入，越来越多的证据指向同自己生活多年的爱人，因此，夫妻二人的猜疑和试探也越加深入，直到妻子在晚餐中无意将自己敏捷的身手暴露给同是内行的杀手丈夫……之后便开始了夫妻之间的疯狂杀戮……
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